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The Effects of Honey on Human Metabolism

“The Effects of Honey on Human Metabolism”
by Ron Fessenden, MD,MPH

Honey consumption at bedtime increases fat metabolism (“fat burning”) during recovery sleep/ Honey, though similar in sugar content to sucrose (table sugar) and  HFCS ( high fructose corn syrup), can be differentiated by its distinctive effects on human metabolism. Part of the differences can be explained by dose and load, however, other differences are unique to honey. These include the following:


partitioning and storage – the consumption of 1-2 tablespoons of honey two to three times per day directly results in liver glycogen formation. Liver glycogen is the primary fuel for the brain during rest and exercise.


Dose and glycemic load –  typical consumption of sugar and HFCS totals the nearly ¾ pound per day for every individual above age 2, an amount which simply overwhelms the liver resulting in elevated blood sugar levels, excessive insulin release, and resultant fat production and storage. (Whereas every cell in the body can metabolize the excessive glucose  load from sucrose and HFCS, only the liver can metabolize fructose)


Honey consumption results in lower blood sugar levels by 20-40% at 60 and 90 minutes post ingestion in a “honey Tolerance Test” versus a Glucose Tolerance Test.


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Honey protects against the elevation in triglycerides that occurs from excessive fructose consumption.

Honey consumption ,by virtue of its lowering (stabilizing) effect on blood sugar, reduces intracellular stress responsible for many of the diseases of aging.


Honey consumption leads to stable liver glycogen which fuels the brain during the night fast and during exercise.

Honey consumption prevents metabolic stress (driven by cortisol and adrenaline) ,thus reducing the risk of the metabolic syndrome and its associated conditions of obesity ,diabetes, cardiovascular disease, osteoporosis, and  neuro-degenerative conditions such as Alzheimers’ Disease and Parkinsonism.


    The most astounding and revolutionary fact relating to honey consumption is that it helps to regulate blood sugar. It prevents hyperglycemia (elevated blood sugar) by removing glucose from the circulation to produce liver glycogen. It prevents hypoglycemia (low blood sugar) by helping to maintain stable liver glycogen levels which may be released as blood sugar falls – a critical factor in controlling hypoglycaemia.

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